DR SOIE PRO& iPS Re: Cream

DR.SOIE PRO & iPS Re: Cream — Senolytic Anti-Aging Cream

An advanced senolytic anti-aging cream developed by dermatology specialists, formulated with iPS Cell Culture Conditioned Medium at the manufacturer’s recommended concentration. Part of DR.SOIE’s PRO & line, this cream is built on the intersection of iPS cell technology and fundamental aging research conducted in collaboration with Hiroo Prime Dermatology Clinic in Tokyo. Unlike conventional anti-aging formulas, it takes a deliberately streamlined approach — free of niacinamide, retinol, and acids — making it an excellent alternative for those sensitive to commonly used active ingredients. The formula focuses on replenishing stem cell potential, restoring intercellular communication, repairing damage, and reducing chronic micro-inflammation. Dense yet non-sticky texture with virtually no scent. Suitable for all skin types with no age restrictions; especially beneficial for skin prone to dryness and dehydration. Can also be used around the eye area.

Key Features
iPS Cell Culture Conditioned Medium — The most advanced cellular ingredient available in skincare. The conditioned medium derived from human fibroblast/mononuclear cell-induced pluripotent stem cell culture improves skin metabolism, restoring cells’ ability to renew at a youthful rate. The medium contains exosomes — molecular communicators that deliver targeted action, addressing the specific types of damage present in your individual skin. Significantly boosts dermal hyaluronic acid synthesis.
Senolytic Action — Lotus Germ Extract + Acetyl Tetrapeptide-2 — Senescent (“zombie”) cells are damaged cells that resist normal clearance by autophagy, accumulate in tissue, and release harmful factors that impair surrounding healthy cells. Lotus Germ Extract acts as a senolytic agent, promoting the clearance of these accumulated senescent cells, while Acetyl Tetrapeptide-2 works synergistically to reduce the chronological aging factor that has until now remained largely beyond the reach of topical skincare.
Heptapeptide-6 for Telomere Protection — Protects telomeres from shortening — a biohacking tool for preserving the youthful potential of cells. Telomere shortening is one of the fundamental mechanisms of chronological cellular aging.
Sphingomonas Culture Extract — Removes defective proteins and reduces chronic micro-inflammation, preventing the cascade of inflammatory signals that accelerate skin aging.
Clean, Streamlined Formula — Ethanol-free, synthetic fragrance-free, mineral oil-free, paraben-free, synthetic colorant-free. Contains no niacinamide, retinol, or acids, offering a gentler alternative for sensitive and reactive skin types.

Contents
30 g (NET WT. 1.0 OZ.)

Manufacturer
DR.SOIE Co., Ltd., supervised by Hiroo Prime Dermatology Clinic. Manufactured by Satis Pharmaceutical Co., Ltd.

Made in Japan

How to Use
After cleansing, prepare the skin with lotion and/or serum. Take 1–2 pearl-sized amounts and gently apply to the entire face, neck, and décolleté. For areas prone to dryness, layer an additional amount.

Ingredients
Water, Dimethicone, BG, Glycerin, Meadowfoam Seed Oil, Phytosteryl/Octyldodecyl Lauroyl Glutamate, Phytosteryl/Isostearyl/Cetyl/Stearyl/Behenyl Dimer Dilinoleate, Diglycerin, Behenyl Alcohol, Phenyl Trimethicone, Diisostearyl Malate, Batyl Alcohol, Stearic Acid, Propanediol, Human (Fibroblast/Mononuclear Cell) Induced Pluripotent Cell Culture Conditioned Medium, Sphingomonas Culture Extract, Acetyl Tetrapeptide-2, Heptapeptide-6, Lotus Germ Extract, Sodium Dilauroyl Glutamate Lysine, Tocopherol, Orange Peel Oil, Brassica Napus (Rapeseed) Seed Oil/Triadica Sebifera (Chinese Tallow Tree) Seed Oil Copolymer, Cetyl Palmitate, Caprylic/Capric/Myristic/Stearic Triglyceride, PEG-75, Isostearyl/Phytosteryl Dimer Dilinoleate, Caprylic/Capric Triglyceride, Lecithin, Xanthan Gum, Ethylhexylglycerin, Biosaccharide Gum-1, Caprylyl Glycol, Carbomer, Phenoxyethanol, Etidronic Acid, Potassium Chloride, Potassium Hydroxide

Precautions
• For external use only. Check that no abnormalities are present on the skin before use.
• Discontinue use if redness, swelling, itching, irritation, loss of color (white spots), darkening, or other abnormalities occur during use or after sun exposure. Continued use may worsen symptoms. Consult a dermatologist if symptoms persist.
• Do not use on skin with wounds, swelling, eczema, or other abnormalities.
• Store away from direct sunlight, high humidity, and extreme temperatures.
• This product contains natural ingredients; color and texture may vary slightly depending on temperature and storage conditions. This does not affect quality.
• Keep out of reach of infants and small children.
• Use as soon as possible after purchase.​​​​​​​​​​​​​​​​