RAISE HC Cream

RAISE Solution HC Cream is a professional-grade rejuvenating cream from Japan’s RAISE skincare line by Central Corporation. Developed in collaboration with Japanese medical research institutions and manufactured by R-Cell Co., Ltd., this intensive cream features a premium stem cell conditioned media extract derived from umbilical cord blood — a naturally rich biological source that is safely collected and processed under strict ethical oversight. No actual stem cells, blood, or tissue are present in the final product; instead, the cream utilizes the beneficial growth factors and proteins that are produced when stem cells are cultivated in a controlled laboratory environment. This culture medium is reported to contain approximately 50 times more GDF-11 (Growth and Differentiation Factor 11) than the adipose (fat) or bone marrow-derived culture media more commonly used in cosmetics, according to the ingredient manufacturer’s comparative data.

Originally developed for use as a finishing treatment in Japanese beauty clinics and luxury aesthetic facilities, RAISE Solution HC Cream combines regenerative skincare technology with a rich, nourishing formula designed to support cellular renewal, improve skin density, and promote a more luminous, youthful-looking complexion. Its concentrated composition means that even periodic use — as infrequently as once every 3 to 7 days alternated with daily products — may support visible improvements in firmness and skin texture.

Key Features

Advanced Stem Cell Culture Technology: The core active in this cream is a conditioned media extract delivered in nanocapsulated form (average capsule size approximately 225 nm). In stem cell skincare, the active ingredient is not the cells themselves but the nutrient-rich culture medium they produce during laboratory cultivation — a solution naturally concentrated with growth factors, signaling proteins, and skin-beneficial compounds. The culture medium used in this product contains elevated levels of ECM (extracellular matrix) substances such as fibronectin and collagen, which are designed to support skin turgor and structural integrity. GDF-11 — a growth and differentiation factor featured in peer-reviewed journals such as Cell, Nature, and Science — is present in this extract and is recognized for its role in promoting fibroblast proliferation and supporting collagen and elastin production.

Active-Type Growth Factor Peptides (EGF & FGF): Contains sh-Oligopeptide-1 (a synthetic human recombinant form of Epidermal Growth Factor / EGF) and sh-Polypeptide-11 (a synthetic human recombinant form of Fibroblast Growth Factor / FGF). These peptides are included in “active-type” nanocapsulated form, designed to support skin cell turnover and stimulate the skin’s natural production of structural proteins.

Acetyl Hexapeptide-8 (Argireline): A well-known peptide recognized for its muscle-relaxant properties in topical skincare. It is designed to help reduce the appearance of expression lines by modulating muscle contraction signals at the skin surface, offering a non-invasive approach to addressing dynamic wrinkles.

Horse Placenta Extract in Nano Double-Liposome Capsules: The placenta extract used in this formula is horse-derived and encapsulated in a nanoscale double-liposome delivery system. Horse placenta is valued in Japanese professional skincare for its rich growth factor and amino acid profile. In this formulation, it is designed to support cellular metabolism and, in combination with α-arbutin, contribute to a brightening effect.

Nano-Encapsulated Soluble Collagen: The collagen in this cream is delivered in nanocapsule form, reducing its molecular weight for improved penetration compared to standard high-molecular-weight collagen. According to manufacturer data, the concentration of collagen within these nanocapsules is approximately 5 times higher than that of conventional collagen formulations.

Triple Hyaluronic Acid Complex: Combines Sodium Hyaluronate for surface hydration, Sodium Acetylated Hyaluronate (super hyaluronic acid) for enhanced moisture retention, and Hydrolyzed Hyaluronic Acid (low molecular weight) for deeper penetration into the skin layers. Together, these three forms are designed to provide multi-layer hydration support.

Triple Ceramide Barrier Complex: Fortified with Ceramide NP, Ceramide AP, and Ceramide EOP — three human-type ceramides that work in concert with Phytosphingosine and Cholesterol to help reinforce the skin’s natural lipid barrier, supporting moisture retention and skin softness.

Antioxidant Complex: Combines Fullerene, Ubiquinone (Coenzyme Q10), Ascorbyl

Tetraisopalmitate (oil-soluble Vitamin C derivative), and Superoxide Dismutase (SOD). Fullerene’s unique spherical molecular structure is recognized for its exceptional free-radical neutralizing capacity. CoQ10 and Vitamin C are encapsulated in nanoparticle form to preserve their activity and enhance delivery.

Brightening Agents: α-Arbutin and Ascorbyl

Tetraisopalmitate (Vitamin C derivative) are included to support a more even, luminous complexion. α-Arbutin is recognized in Japanese cosmetics for its gentle yet effective approach to managing the appearance of uneven skin tone.

Pinus Pinaster Bark Extract (French Maritime Pine Bark / Pycnogenol): A natural extract with recognized antioxidant and skin-conditioning properties, traditionally valued for its role in supporting circulation and helping to refine the appearance of enlarged pores.

Licorice Root Complex: Contains both Glycyrrhiza Glabra (Licorice) Root Extract and Dipotassium Glycyrrhizate, providing natural anti-inflammatory and skin-soothing properties to complement the cream’s active ingredient profile.

Comprehensive Amino Acid Profile: Includes 15 amino acids — Taurine, Glutamic Acid, Leucine, Lysine, Glycine, Histidine, Serine, Valine, Threonine, Phenylalanine, Alanine, Isoleucine, Arginine, Proline, and Tyrosine — designed to support the skin’s natural protein synthesis and moisture balance.

Additional Skin-Conditioning Ingredients: Squalane for emollient protection, Polyquaternium-51 (Lipidure) for biomimetic moisture retention, Allantoin for soothing, Cyanocobalamin (Vitamin B12) for supporting cellular respiration and contributing to the cream’s characteristic pink tint, and Theobroma Cacao (Cocoa) Seed Butter for nourishment and the cream’s rich texture.

Contents: 30g 

Manufacturer: Central Corporation (manufactured by R-Cell Co., Ltd.)

Made in Japan
This premium skincare product is manufactured in Japan under strict quality control standards in collaboration with Japanese medical research institutions.

How to Use

1. Cleanse and apply toner or serum as part of your usual routine
2. Take a pea-sized amount using the included spatula
3. Warm the cream between your palms by rubbing your fingertips together — the rich texture melts with body heat
4. Apply to face and neck using gentle pressing motions with warm hands
5. Use as the final step in your skincare routine, ideally as a night treatment
6. For intensive care, use daily; the concentrated formula is also effective when used once every 3 to 7 days alternated with lighter daily products

Storage

Store in a cool place away from direct sunlight and extreme temperatures. Keep the container opening clean after each use and close the lid securely. Keep out of reach of children.

Ingredients

Water, Ethylhexyl Palmitate, Glyceryl Stearate (SE), Dipropylene Glycol, Behenyl Alcohol, Glycerin, Pentylene Glycol, Polysorbate 60, Glyceryl Stearate, Theobroma Cacao (Cocoa) Seed Butter, Caprylic/Capric Triglyceride, Human Umbilical Cord Blood Cell Conditioned Media Extract, sh-Oligopeptide-1, sh-Polypeptide-11, Placenta Extract, Glycyrrhiza Glabra (Licorice) Root Extract, Soluble Collagen, Dipentaerythrityl Hexa(Hydroxystearate/Stearate/Rosinate), Cetyl Palmitate, Sorbitan Stearate, Dimethicone, Squalane, Alpha-Arbutin, Sodium Hyaluronate, Sodium Acetylated Hyaluronate, Hydrolyzed Hyaluronic Acid, Taurine, Glutamic Acid, Leucine, Lysine HCl, Glycine, Histidine HCl, Serine, Valine, Sodium Aspartate, Threonine, Allantoin, Phenylalanine, Alanine, Isoleucine, Arginine, Proline, Tyrosine, Disodium Inosinate, Disodium Guanylate, Pinus Pinaster Bark Extract, Superoxide Dismutase, Dipotassium Glycyrrhizate, Cyanocobalamin, Ceramide NP, Ceramide AP, Ceramide EOP, Phytosphingosine, Sodium Lauroyl Lactylate, Carbomer, Xanthan Gum, Ascorbyl Tetraisopalmitate, Cerebrosides, Ubiquinone, Fullerenes, PVP, Acetyl Hexapeptide-8, Polyquaternium-51, Glycine Soja (Soybean) Seed Extract, Sodium Phosphate, Lecithin, Hydrogenated Lecithin, Butylene Glycol, Polyglyceryl-10, Propanediol, Glyceryl Palmitate, 1,2-Hexanediol, Cholesterol, Tocopherol, Phenoxyethanol​​​​​​​​​​​​​​​​